What to Do About Vitamin A Toxicity | Chris Masterjohn Lite #126

What to Do About Vitamin A Toxicity | Chris Masterjohn Lite #126

Vitamin A toxicity. Here is what to do. Hi. I’m Dr. Chris Masterjohn of chrismasterjohnphd.com, and this is Chris Masterjohn Lite, where the name of the game is “Details? Shmeetails. Just tell me what works!” And today we’re going to talk about what to do about vitamin A toxicity. In the last episode we covered how to know if you’re vitamin A-toxic. So, here is what are we going to do about it. So, the first thing is figure out what the likelihood is that you have a serious problem. Because if you have a serious problem, you should see a doctor, but if you’ve been taking 10,000 IU of vitamin A for quite a long time and you have headaches and you’re speculating that maybe the headaches are caused by too much of vitamin A, then I think you can take out the vitamin A and see if they resolve and follow the other recommendations I’m about to make without going to see a doctor. Simply because the likelihood that you have any serious vitamin A toxicity is extraordinarily low. On the other hand, if you went through the points in the last episode and you say, “Okay, I have signs and symptoms of vitamin A toxicity, my blood work seems to support it, and I’ve actually been taking doses that make it plausible that I have a serious problem,” then you should definitely see a doctor. Because even though a headache can be resolved quite easily on your own, you could have serious problems in your liver or other organs where you’re doing damage that has caused the need to be addressed with medicine. So, you want to rule out that you have serious problems. And if you do, if you do have serious problems, you want to get them addressed with the proper medical care. Now, with that said, what I think is reasonable to do as a strategy regardless of what medical treatment might be needed is number one, take out the vitamin A supplements. Number two, if you have vitamin A-rich foods, particularly liver, take them out, but when you do so, be very mindful of the other nutrients that the liver is supplying and go through the checklist to see how you’re making up for that with the other foods in your diet. And then number three, I would say add supplements of the other fat-soluble vitamins. The reason for this is that all of the fat-soluble vitamins are broken down and excreted in the urine by similar or even the same metabolic machinery. So, there’s a degree to which excess amounts of any one fat-soluble vitamin will encourage the breaking down and elimination of the others. You don’t want to add just vitamin D, or just vitamin K, or just vitamin E because then you will not only encourage the breaking down of the vitamin A, but you’ll also encourage the breaking down of whatever is missing in the — in the supplements. So, what you do want to do is supplement vitamin D, vitamin E, and vitamin K. What doses to use, what ratios? I’m doing a little bit of guesswork here, but based on trying to keep them within the same level of the degree of excess over the typical requirements, I would say that your ratio should be about 400 IU of alpha-tocopherol form of vitamin E that can definitely also include mixed tocopherols and even tocotrienols in the background. But the amount of alpha-tocopherol to shoot for I would say would be 400 IU. One milligram of vitamin K2 as menaquinone-4. And 4000 IU of vitamin D. I would just keep it to those amounts if you’re going to do this on your own. If you’re going to work with a qualified healthcare practitioner to monitor the levels of all of these vitamins, then I think it’s safe to use those ratios, but double or triple the amounts to see what’s most effective at reducing your levels of vitamin A and reducing other markers, as well as the signs and symptoms of vitamin A toxicity while not going overboard in creating toxic amounts of any of the other nutrients. This episode is brought to you by Ancestral Supplements living collagen. Our Native American ancestors believed that eating the organs from a healthy animal would support the health of the corresponding organ of the individual. Ancestral Supplements has a nose-to-tail product line of grass-fed liver, organs, living collagen, bone marrow, and more. All in the convenience of a capsule. For more information or to buy any of their products, go to ancestralsupplements.com. This episode is brought to you by Ample. Ample is a meal in a bottle that takes a total of two minutes to prepare, consume, and clean up. It provides a balance of fat, protein, and carbs plus all the vitamins and minerals you need in a single meal. All from a blend of natural ingredients. It’s available in original, vegan, and keto versions portioned as either 400 or 600 calories per meal. I’m an advisor to Ample, and I use it to save time when I’m working on major projects on a tight schedule. It keeps my brain going while I power through the day, never letting food prep get in the way of my productivity. Head to amplemeal.com and enter the promo code: CHRIS15 at checkout for a 15% discount off your first order. For ad-free versions of these episodes with transcripts that you can read and getting early access to the episodes often weeks or maybe even months ahead of time, you can sign up for the CMJ Masterpass at chrismasterjohnphd.com/masterpass and use the code: LITE10 to get ten% lifetime discount. The audio of this episode was enhanced and post-processed by Bob Davodian of Taurean Mixing. You can find more of his work at taureanonlinemixing.com. All right, I hope you found this useful. Signing off, this is Chris Masterjohn of chrismasterjohnphd.com. This has been Chris Masterjohn Lite, and I will see you in the next episode.



  • TaleofPucca

    Thank you!

  • Jill Philips

    “Please The Foundation Of All Our Foods And Medicine Supplements begins in our honest
    Knowledge of the WATERS Soil Seeds Plants and animals fertilizer and Truth in Ripe On The vines and storage Processing That does not deplete Their Nutrients:

  • A

    after two weeks taking 25k ui of a acetate, i can see my dry eyes have resolved, i no longer see yellow spots when in plain sun and i see much better in the dark. i have also aplied retinol on the skin 1,5% cream a few days. in total i took 400k oraly and i guess much less on the skin. i feel a little tired and a very small nausea sometimes in the afternoon. how probable this is from overdose? maybe the retinyl acetate form is too much ? other question, i have a 7 months old fracture of the malleolus that never calcified on radio and still hurts. is it possible that a lack of vitamin a could cause non healing of the bone? i took much vitamin d and k2 in the two forms and vitamin e right before and after my fracture, but never took vitamin a or liver. i began feeling pain in my eyes a few months before my fracture and untill i suplemented with vitamin a two weeks ago. i know vitamin a in excess may weeken bones but could it have oposide efect if deficient or help heal fractures if someone is in need ? thanks.

  • mister E

    Matt Stone of 180 Degree Health is currently exploring the idea that vitamin-A intake is promoting the diseases of modern society. Personally I don't see it, but Matt Stone does hold some valuable insights.

  • Juan Marquez

    Yo Dr schmetails, I recently commented on your video about copper and vitamin C. Can you please review my comment and provide any feedback about my questions? I really enjoy watching your videos btw. Hope to hear from you soon. Thank you!

  • Ben Nguyen

    Regarding supplementing with 400 IU of d-alpha/mixed tocopherol.. any thoughts on the work of Dr. Barrie Tan who suggests that unlike tocotrienols, alpha-tocopherol requires a transport-protein.. thus any excess Vitamin E in this form, will wind up as a pro-oxidant on the LDL! He was on the Ben Greenfield podcast (see 41min mark).

    He also mentions how in 2019 the FDA switched from I.U. to milligrams, and how this favors the less desirable tocopherols (10mg alpha tocopherol = 10 IU, 10mg gamma tocopherol = 1 IU, 10mg tocotrienols = 0 IU)

    Finally Dr. Tan recommends 15mg from food.. or his labs (DesignsForHealth) Delta/Gamma tocotrienols, which comes from the flesh of the annatto seeds of the achiote/achuete (Bixa orellana) lipstick tree.. it also has some Geraniol Geranial which may help offset the negative effects of statins.

  • Harvey Morgan

    I eat like 3 lb of beef liver a week, am i fudged? LOL

  • 1111

    Seriously, how many people are at risk for toxicity??? The levels for toxicity are ridiculously high but toxicity fear has kept me from taking it for years. Fuck that. I would need to take over 3 bottles of 10,000 IU DAILY for 6-15 months to be getting too much. Stop the Vitamin A fear mongering.

    Acute vitamin A toxicity may occur with a single ingestion of 25,000 IU/kg or more. Signs and symptoms include nausea, vomiting, diarrhea, dizziness, lethargy, drowsiness, increased intracranial pressure, and skin changes such as erythema, pruritus, or desquamation.

    Chronic vitamin A toxicity may occur with excessive ingestion of 4000 IU/kg or more daily for 6-15 months.


  • iloverumi

    thanks for info

  • Ash Tailor

    I love the video, it’s v informative.
    I was prescribed Roaccutane for 7 months
    Am off Roaccutane for 5 months now but only this month my joint started clicking tho from February I have had joint pains , bone pains n inflammation
    Can u suggest what I can do which will help me .. any suggestion would be appreciated

  • King Art Music

    I just took a vitamin a serum test and my vitamin A levels were high. Normal range is 18.9 to 57.3 and I’m at 115. Thanks for the advice I will stop taking my multivitamin which has 10,000 I use in it.

  • Bob Dylan

    HaHa, I thought this was a brand new video. 😉 😉

  • Phillip Jacowski

    1. Nobody is eating liver. 2. Thank you. 3. I have vitaminosis A from retin-a, adapalene, and retinoic acid and the past 8 days have been a living hell. Thank you so much for sharing this

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