Putrefying Protein and “Toxifying” Enzymes

Putrefying Protein and “Toxifying” Enzymes

“Putrefying Protein and ‘Toxifying’ Enzymes” Colon cancer is a leading cancer killer,
yet there’s this paradox in Africa where they rarely get the
disease even in modern times when they are no longer eating
their traditional whole food diet. So they’re no longer eating lots of fiber
and fresh fruits and vegetables. It is likely, therefore, that their continued
low prevalence of colon cancer — 50 times lower than ours — is related to their low intake
of animal protein and fat as I explored previously. But why would animal protein
and fat increase cancer risk? Well, as I noted in Bowel Wars,
if you eat egg whites, for example, some of the protein isn’t
digested, isn’t absorbed, and ends up in our colon,
where it undergoes a process called putrefaction. When animal protein putrefies in
the gut, it can lead to the production of the rotten egg gas, hydrogen
sulfide, which, over and above its objectionable odor, can produce
changes that increase cancer risk. Putrefying protein also
produces ammonia. Over a lifetime on a standard Western
diet, the bacteria in our colon may release the amount of ammonia
found in a thousand gallons of Windex. At concentrations found
day-to-day inside the colon on usual Western diets, ammonia
destroys cells, alters DNA synthesis, increases cellular proliferation,
may increases virus infection, favor the growth of cancerous
cells, and evidently increase virus infections a second time. And it’s the products of protein and
fat digestion that are to blame, such that you can double
ammonia concentrations in the colon by eating
a lot of meat. But put people on a plant-based
diet, and within just one week the enzyme activity that creates the
ammonia in the colon drops like a rock. Other bacterial enzymes
are affected as well. Remember how broccoli
family vegetables can boost detoxifying
enzymes in the liver? These so called phase 2 enzymes,
UDP-glucuronosyltransferases, they detoxify drugs and chemicals by
applying a chemical straightjacket, here shown in red, deactivating
the date rape drug GHB, or taking the carcinogens
in meat like benzopyrene and rendering them harmless
before dumping them back into the intestine for disposal. But if our liver detoxifies it,
why is benzopyrene in meat still associated with rectal cancer? Well, certain bacteria in our
gut contain the opposite enzyme, a ‘toxifying’ enzyme that
removes the straightjacket and frees the carcinogen to wreak a last bit of havoc before
it leaves the body. But within one week
of eating plant-based, we can drop that enzyme
activity in our colon by about 30%. But this was with a raw,
‘extreme’ vegan diet. What about a regular vegetarian diet? Compared to a pound-of-meat-a-day diet,
those placed on a meat-free diet for a month experienced a
70% drop in ‘toxifying’ activity, which may raise the amount of
carcinogens, within the colon. And long-time vegetarians exhibit just
a fraction of carcinogen-releasing activity compared to those on a
standard American diet. So this may all help explain the
increased risk in the United States. Researchers put it
to the test, though, by taking biopsies from
the lining of the colons of Americans versus Africans,
to measure proliferation rates, how fast the cells are dividing,
a marker for increased cancer risk, and decreased cancer survival. This is what they found. The black dots denote proliferating cells,
which we can see throughout the colons of Caucasian-Americans
and African-Americans, but only a few were seen
in the African biopsies. Dramatically lower proliferation rates. Overall, higher colorectal cancer risk was
associated with higher dietary intakes of animal products and
higher colonic populations of potentially toxic hydrogen and
secondary bile-salt-producing bacteria. And while they were
in there to get biopsies, they looked around a little bit, and out
of all the African colons they looked at, they only detected four
issues out of 18 colons. But out of the 17 African American
or Caucasian colons they found 21 problems each: polyps,
diverticulosis, lots of hemorrhoids. The remarkably pristine condition
of the colons of our African volunteers further supports our impression
that African colons were, in general, far healthier
than American colons.



  • elite1980s

    2:04 These doctors and scientist's minds in having to remember the name/spelling and meaning of such things as UPD-glucuronosyltransferases is simply amazing.

  • chickpea

    I would love it if you could do a timeline video, like the kind my mum used to have on the fridge for quitting smoking (after 1 week this happens, after one month you get this benefit, after 10 years you are the same as a non-smoker or whatever) but for veganism. It would be a real incentive for vegans who are primarily in it for the health benefits. Or if this already exists somewhere, I would like to know about it!


    nothing quite like a pristine colon

  • farm country

    "futurevideo10" apparently gets paid by the pound (of BS). I answered his initial posts in case he was just mistaken, but learned he deliberately omits facts inconvenient to his argument. That is called propaganda. I assume he is a shill paid by someone who sells animal products or pills who would lose a lot of revenue if people learned the truth. Personally, it takes a real piece of work to anonymously spam an internet site to discourage people from learning nutrition science to improve their health. What a true dirt bag this guy is.

  • Kevin Smith


  • balderdashery G

    Future Video just got owned! Yeeeessssss!

  • Joe Grant

    Dr. Greger could you please do a video explaining the truth about soy? There is do much controversy about it causing hormonal imbalances and all sorts of unnatural things but I've been eating soy since I've been eating plant based I would love to clear this up once and for all!

  • TheCryptoCoinist

    i wish i could be vegan

  • vane brin

    Dr. Greger when are you making a video about Helicobacter Pyloris or GERD? thanks!! Im a post VSG and new vegan low fat patient and im suffering with this two issues. Will love to get your findings on these.

  • Marcus Triton

    great vid. TY.

  • consumedbyfire13

    Try cooking some ground beef on the stove and let the fat sit for a few hours, and then look at it. It's so sticky and I would even call it putrid. I would imagine it takes a lot of fiber and a good digestive system to get that out of your system in a timely manner. It's quite a disgusting thought.

  • consumedbyfire13

    So by this study, it sounds to me that you are just pointing to meat and not dairy products.

  • TheJadeFist

    Lol you know the entire time, I couldn't help but wonder, who actually volunteers for this kind of study.

  • Sophia Shakti

    the answer is simple – you have to have regular bowel movements. No to constipation, foundation for colon therapy – irrigation. So, what the benefits are coming from? Being regular or constipated?

  • Andrew Harvey

    Amazing. Despite all of these veg-head videos describing how meat will kill you, vegetarians still don't live any longer than non-vegetarians. Anyone care to explain?

  • Flash Man

    It's no surprise that Africans have nice butts 😁

  • Kathy Fausett

    Bottom line——walk right past the dead animal section of the grocery store.

  • Richard Curtin

    This video should have 100.000's of thousands of hits. Sad …only 43,000 after 1 year. NO wonder we're one of sickest countries in the world. Keep up the great work Dr G!!!!!!!

  • Vamavid

    Colon Power

  • Chris Tste

    Why is Dave Mustaine the narrator?

  • Troy Russell

    Where in Africa?

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